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Evaluating Bezlotoxumab-Fidaxomicin Combination Therapy in Clostridioides Infection: A Single-Center Retrospective Study from Aichi Prefecture, Japan

<b>Background/Objectives:</b> <i>Clostridioides difficile</i> infection (CDI) poses a significant healthcare challenge, with recurrence rates reaching 30%, leading to substantial morbidity and costs. Fidaxomicin (FDX) and bezlotoxumab (BEZ) have shown potential in reducing recurrence; however, real-...

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Principais autores: Jun Hirai, Nobuaki Mori, Yuki Hanai, Nobuhiro Asai, Mao Hagihara, Hiroshige Mikamo
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-02-01
Serier:Antibiotics
Fag:
bezlotoxumab
fidaxomicin
combination therapy
<i>Clostridioides difficile</i>
recurrence
severe diarrhea
Online adgang:https://www.mdpi.com/2079-6382/14/3/228
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