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The HDAC/HSP90 Inhibitor G570 Attenuated Blue Light-Induced Cell Migration in RPE Cells and Neovascularization in Mice through Decreased VEGF Production

Age-related macular degeneration (AMD) occurs due to an abnormality of retinal pigment epithelium (RPE) cells that leads to gradual degeneration of the macula. Currently, AMD drug pipelines are endowed with limited options, and anti-VEGF agents stand as the dominantly employed therapy. Despite the p...

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Principais autores: Tai-Ju Hsu, Kunal Nepali, Chi-Hao Tsai, Zuha Imtiyaz, Fan-Li Lin, George Hsiao, Mei-Jung Lai, Yu-Wen Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2021-07-01
Colecção:Molecules
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Acesso em linha:https://www.mdpi.com/1420-3049/26/14/4359
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