Multiparametric senescent cell phenotyping reveals targets of senolytic therapy in the aged murine skeleton
Abstract Senescence drives organismal aging, yet the deep characterization of senescent cells in vivo remains incomplete. Here, we apply mass cytometry by time-of-flight using carefully validated antibodies to analyze senescent cells at single-cell resolution. We use multiple criteria to identify se...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Portfolio
2023-07-01
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| Seria: | Nature Communications |
| Dostęp online: | https://doi.org/10.1038/s41467-023-40393-9 |
| Etykiety: |
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