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SNX9-induced membrane tubulation regulates CD28 cluster stability and signalling

T cell activation requires engagement of a cognate antigen by the T cell receptor (TCR) and the co-stimulatory signal of CD28. Both TCR and CD28 aggregate into clusters at the plasma membrane of activated T cells. While the role of TCR clustering in T cell activation has been extensively investigate...

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Bibliografische gegevens
Hoofdauteurs: Manuela Ecker, Richard Schregle, Natasha Kapoor-Kaushik, Pascal Rossatti, Verena M Betzler, Daryan Kempe, Maté Biro, Nicholas Ariotti, Gregory MI Redpath, Jeremie Rossy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications Ltd 2022-01-01
Reeks:eLife
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Online toegang:https://elifesciences.org/articles/67550
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