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mRNA codon optimization with quantum computers

Reverse translation of polypeptide sequences to expressible mRNA constructs is a NP-hard combinatorial optimization problem. Each amino acid in the protein sequence can be represented by as many as six codons, and the process of selecting the combination that maximizes probability of expression is t...

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Bibliografiset tiedot
Päätekijät: Dillion M. Fox, Kim M. Branson, Ross C. Walker
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science (PLoS) 2021-01-01
Sarja:PLoS ONE
Linkit:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555812/?tool=EBI
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