YAP Inhibits HIV-1 transcription and promotes HIV-1 latency by regulating E3 ubiquitin ligase UHRF1 mediated tat degradation.

The latency of human immunodeficiency virus type 1 (HIV-1) is a major barrier to achieving an HIV-1 cure, as antiretroviral therapy does not target the latent virus. Virus-host interactions play an essential role in various stages of the HIV-1 lifecycle. Exploring the interaction between host factor...

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Detalhes bibliográficos

Principais autores:	Chenliang Zhou, Hong He, Yuzai Zhang, Xiaolian Liu, Muye Xia, Jiayin Qiu, Ziyao Wu, Huba Khamis Rashid, Wenli Liu, Jie Peng, Lin Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2026-01-01
coleção:	PLoS Pathogens
Acesso em linha:	https://doi.org/10.1371/journal.ppat.1013906
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