Dual-tracer autoradiographic analysis of glucose metabolism and hypoxia in orthotopic and PDX tumor models

Background and purpose: Quantification/mapping of tumor hypoxia may guide pretreatment decision-making in radiation oncology. Hypoxia-selective positron emission tomography (PET) tracers, like 18F-fluoroazomycin arabinoside (FAZA), allow assessment of hypoxia, but since hypoxia stimulates glycolysis...

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Autori principali:	Morten Busk, Martin K Thomsen, Jens Overgaard, Martin F Berthelsen, Henrik Hager, Johan Bussink, Kim V Hansen, Steen Jakobsen, Jacob Kinggaard Lilja-Fischer, Ebbe Boedtkjers, Mikkel H Vendelbo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Medical Journals Sweden 2025-08-01
Serie:	Acta Oncologica
Soggetti:	hypoxia radioresistance image-guided radiotherapy PET FDG FAZA
Accesso online:	https://medicaljournalssweden.se/actaoncologica/article/view/44002
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