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Infectious outcomes of a standardized subcutaneous immunoglobulin dose reduction strategy in primary immune deficiencies amid global shortage

IntroductionImmunoglobulin replacement therapy (IgRT), either intravenous (IVIg) or subcutaneous (SCIg), is crucial for managing primary immune deficiencies (PIDs) with hypogammaglobulinemia by reducing infection rates and mortality. During the COVID-19 pandemic, a global shortage of SCIg prompted o...

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Principais autores: Pedro Moral Moral, Marta Dafne Cabanero-Navalon, Paula Teresa López-León, Héctor Balastegui-Martín, Sandra Martínez Mercader, Amparo Mir, Victor Garcia-Bustos
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-01-01
Serier:Frontiers in Immunology
Fag:
immunoglobulin replacement therapy
humoral primary immune deficiencies
subcutaneous immunoglobulin
infections
cost-effectiveness
resource shortage
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1527514/full
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