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Application of Minimal Physiologically-Based Pharmacokinetic Model to Simulate Lung and Trachea Exposure of Pyronaridine and Artesunate in Hamsters

A fixed-dose combination of pyronaridine and artesunate, one of the artemisinin-based combination therapies, has been used as a potent antimalarial treatment regimen. Recently, several studies have reported the antiviral effects of both drugs against severe acute respiratory syndrome coronavirus two...

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Збережено в:
Бібліографічні деталі
Автори: Dong Wook Kang, Kyung Min Kim, Ju Hee Kim, Hea-Young Cho
Формат: Artigo
Мова:Inglês
Опубліковано: MDPI AG 2023-03-01
Серія:Pharmaceutics
Предмети:
Онлайн доступ:https://www.mdpi.com/1999-4923/15/3/838
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