Crk adaptors negatively regulate actin polymerization in pedestals formed by enteropathogenic Escherichia coli (EPEC) by binding to Tir effector.

Infections by enteropathogenic Escherichia coli (EPEC) cause diarrhea linked to high infant mortality in developing countries. EPEC adheres to epithelial cells and induces the formation of actin pedestals. Actin polymerization is driven fundamentally through signaling mediated by Tir bacterial effec...

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Ngā kaituhi matua:	Elvira Nieto-Pelegrin, Eugenia Meiler, José Manuel Martín-Villa, María Benito-León, Narcisa Martinez-Quiles
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Public Library of Science (PLoS) 2014-03-01
Rangatū:	PLoS Pathogens
Urunga tuihono:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1004022&type=printable
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