Microglia depletion diminishes key elements of the leukotriene pathway in the brain of Alzheimer’s Disease mice
Abstract Leukotrienes (LTs) contribute to the neuropathology of chronic neurodegenerative disorders including Alzheimer’s Disease (AD), where they mediate neuroinflammation and neuronal cell-death. In consequence, blocking the action of Leukotrienes (LTs) ameliorates pathologies and improves cogniti...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2020-08-01
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| Serie: | Acta Neuropathologica Communications |
| Soggetti: | |
| Accesso online: | http://link.springer.com/article/10.1186/s40478-020-00989-4 |
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