The v8-10 variant isoform of CD44 is selectively expressed in the normal human colonic stem cell niche and frequently is overexpressed in colon carcinomas during tumor development

CD44 protein and its variant isoforms are expressed in cancer stem cells (CSCs), and various CD44 isoforms can have different functional roles in cells. Our goal was to investigate how different CD44 isoforms contribute to the emergence of stem cell (SC) overpopulation that drives colorectal cancer...

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Hlavní autoři:	Bruce M. Boman, Vignesh Viswanathan, Caroline O. B. Facey, Jeremy Z. Fields, James W. Stave
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis Group 2023-12-01
Edice:	Cancer Biology & Therapy
Témata:	cd44 protein cd44v8-10 cd44 variant isoforms cancer stem cells colorectal cancer
On-line přístup:	http://dx.doi.org/10.1080/15384047.2023.2195363
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