IGF2BP3 curbed by miR-15c-3p restores disrupted lipid storage and progesterone secretion in chicken granulosa cells under oxidative stress through AKT-Raf1-ERK1/2 signaling pathway

For commercial laying hens, the continuous high-intensity ovulation process leads to a significant accumulation of reactive oxygen species (ROS) in the granulosa cells, inducing oxidative stress, which accelerates ovarian aging and shortens the peak laying period. The molecular mechanisms underlying...

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Autori principali:	Zhongzhen Lin, Yanrong Gong, Chunlin Yu, Chaowu Yang, Lingqian Yin, Donghao Zhang, Yuan Tang, Feng Xu, Ye Wang, Yiping Liu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2025-02-01
Serie:	Poultry Science
Soggetti:	Lipid metabolism Steroid hormone Fecundity Poultry
Accesso online:	http://www.sciencedirect.com/science/article/pii/S0032579124013397
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