Pristimerin as a Novel Hepatoprotective Agent Against Experimental Autoimmune Hepatitis

Pristimerin (Pris) is bioactive natural quinonoid triterpene that has anti-inflammatory and anti-cancer activities. Meanwhile, its effect against hepatitis needs to be elucidated. This investigation aimed to evaluate the ability of Pris to protect against autoimmune hepatitis (AIH). A mouse model of...

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Autors principals:	Dina S. El-Agamy, Ahmed A. Shaaban, Hamdi H. Almaramhy, Sarah Elkablawy, Mohamed A. Elkablawy
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2018-03-01
Col·lecció:	Frontiers in Pharmacology
Matèries:	pristimerin hepatitis nuclear factor erythroid-related factor 2 (Nrf2) hemeoxygenase-1 nuclear factor kappa-B apoptosis
Accés en línia:	http://journal.frontiersin.org/article/10.3389/fphar.2018.00292/full
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