Arginase-1-expressing macrophages suppress Th2 cytokine-driven inflammation and fibrosis.
Macrophage-specific expression of Arginase-1 is commonly believed to promote inflammation, fibrosis, and wound healing by enhancing L-proline, polyamine, and Th2 cytokine production. Here, however, we show that macrophage-specific Arg1 functions as an inhibitor of inflammation and fibrosis following...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science (PLoS)
2009-04-01
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| Col·lecció: | PLoS Pathogens |
| Accés en línia: | http://europepmc.org/articles/PMC2660425?pdf=render |
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