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Phospholipase B Is Critical for Cryptococcus neoformans Survival in the Central Nervous System

ABSTRACT Cryptococcus neoformans (Cn) is an opportunistic, encapsulated, yeast-like fungus that causes severe meningoencephalitis, especially in countries with high HIV prevalence. In addition to its well-known polysaccharide capsule, Cn has other virulence factors such as phospholipases, a heteroge...

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Principais autores: Mohamed F. Hamed, Glauber Ribeiro de Sousa Araújo, Melissa E. Munzen, Marta Reguera-Gomez, Carly Epstein, Hiu Ham Lee, Susana Frases, Luis R. Martinez
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2023-04-01
Serier:mBio
Fag:
cerebral cryptococcosis
Cryptococcus neoformans
glia
GXM
nitric oxide
phospholipase
Online adgang:https://journals.asm.org/doi/10.1128/mbio.02640-22
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