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Progresses in overcoming the limitations of in vitro erythropoiesis using human induced pluripotent stem cells

Abstract Researchers have attempted to generate transfusable oxygen carriers to mitigate RBC supply shortages. In vitro generation of RBCs using stem cells such as hematopoietic stem and progenitor cells (HSPCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) has shown promi...

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Principais autores: Hyeonwoo Ju, Yeowon Sohn, Yoojun Nam, Yeri Alice Rim
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2024-05-01
Series:Stem Cell Research & Therapy
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Acceso en liña:https://doi.org/10.1186/s13287-024-03754-9
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