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Synthesis and properties of a selective inhibitor of homeodomain-interacting protein kinase 2 (HIPK2).

Homeodomain-interacting protein kinase 2 (HIPK2) is a Ser/Thr kinase controlling cell proliferation and survival, whose investigation has been hampered by the lack of specific inhibitors able to dissect its cellular functions. SB203580, a p38 MAP kinase inhibitor, has been used as a tool to inhibit...

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Hlavní autoři: Giorgio Cozza, Sofia Zanin, Renate Determann, Maria Ruzzene, Conrad Kunick, Lorenzo A Pinna
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2014-01-01
Edice:PLoS ONE
On-line přístup:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089176&type=printable
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