Ionizing Radiation Induces Endothelial Inflammation and Apoptosis via p90RSK-Mediated ERK5 S496 Phosphorylation

Adverse cardiovascular events are a leading nonmalignant cause of morbidity and mortality among cancer survivors who have been exposed to ionizing radiation (IR), but the exact mechanism of the cardiovascular complications induced by IR remains unclear. In this study we investigated the potential ro...

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Detalhes bibliográficos

Principais autores:	Hang Thi Vu, Sivareddy Kotla, Kyung Ae Ko, Yuka Fujii, Yunting Tao, Jan Medina, Tamlyn Thomas, Megumi Hada, Anil K. Sood, Pankaj Kumar Singh, Sarah A. Milgrom, Sunil Krishnan, Keigi Fujiwara, Nhat-Tu Le, Jun-Ichi Abe
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2018-03-01
coleção:	Frontiers in Cardiovascular Medicine
Assuntos:	Ionizing radiation p90RSK ERK5 EC inflammation EC apoptosis
Acesso em linha:	http://journal.frontiersin.org/article/10.3389/fcvm.2018.00023/full
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