Epigenome editing of the potential enhancers of the schizophrenia risk genes: approaches for optimization of the genetic constructs

Hereditary factors contribute significantly to the development of schizophrenia. However, despite many years of research, the genetic architecture and mechanisms of the participation of genetic factors in the development of schizophrenia are not well understood. Genome-wide analyzes of genetic assoc...

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Главные авторы:	D. A. Abashkin, A. O. Kurishev, S. V. Smirnova, D. S. Karpov, V. E. Golimbet
Формат:	Artigo
Язык:	Russo
Опубликовано:	Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation 2019-12-01
Серии:	Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева
Предметы:	schizophrenia, enhancers, crispr / spycas9
Online-ссылка:	https://www.bekhterevreview.com/jour/article/view/324
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