Degradation rates and products of fluticasone propionate in alkaline solutions

The apparent degradation rate constant of fluticasone propionate (FLT) in 0.1 M NaOH:methanol=1:1 at 37 °C was previously reported to be 0.169±0.003 h−1, and four degradation products (products 1–4) were observed in the solution. The aims of the present study were to assess the degradation rates of...

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Principais autores:	Tadakazu Tokumura, Naoko Yoshida, Kanami Mori-Yasumoto, Osamu Shirota, Takuro Kurita
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2017-10-01
Serija:	Journal of Pharmaceutical Analysis
Teme:	Fluticasone propionate Degradation rate Degradation products Chemical structure Alkaline solution
Online dostop:	http://www.sciencedirect.com/science/article/pii/S2095177917300230
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