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The ACBD3 protein coordinates ER-Golgi contacts to enable productive TBEV infection

ABSTRACT Flavivirus infection involves extensive remodeling of the endoplasmic reticulum (ER), which is key to both the replication of the viral RNA genome as well as the assembly and release of new virions. However, little is known about how viral proteins and host factors cooperatively facilitate...

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Principais autores: Wai-Lok Yau, Marie B. A. Peters, Sebastian Rönfeldt, Marie N. Sorin, Richard Lindqvist, Lauri I. A. Pulkkinen, Lars-Anders Carlson, Anna K. Överby, Richard Lundmark
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2025-05-01
Series:Journal of Virology
Assuntos:
Orthoflavivirus
flavivirus
NS4B
ACBD3
host-pathogen interaction
replication organelles
Acceso en liña:https://journals.asm.org/doi/10.1128/jvi.02224-24
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