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Dscam1 Forms a Complex with Robo1 and the N-Terminal Fragment of Slit to Promote the Growth of Longitudinal Axons.

The Slit protein is a major midline repellent for central nervous system (CNS) axons. In vivo, Slit is proteolytically cleaved into N- and C-terminal fragments, but the biological significance of this is unknown. Analysis in the Drosophila ventral nerve cord of a slit allele (slit-UC) that cannot be...

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Váldodahkkit: Maryam Alavi, Minmin Song, Gracie L Andrews King, Taylor Gillis, Robert Propst, Matthew Lamanuzzi, Adam Bousum, Amanda Miller, Ryan Allen, Thomas Kidd
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2016-09-01
Ráidu:PLoS Biology
Liŋkkat:https://doi.org/10.1371/journal.pbio.1002560
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