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Structural visualization of key steps in nucleosome reorganization by human FACT

Abstract Facilitates chromatin transcription (FACT) is a histone chaperone, which accomplishes both nucleosome assembly and disassembly. Our combined cryo-electron microscopy (EM) and native mass spectrometry (MS) studies revealed novel key steps of nucleosome reorganization conducted by a Mid domai...

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Bibliografiske detaljer
Principais autores: Kouta Mayanagi, Kazumi Saikusa, Naoyuki Miyazaki, Satoko Akashi, Kenji Iwasaki, Yoshifumi Nishimura, Kosuke Morikawa, Yasuo Tsunaka
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2019-07-01
Serier:Scientific Reports
Online adgang:https://doi.org/10.1038/s41598-019-46617-7
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