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Impact of TP53 mutations in acute myeloid leukemia patients treated with azacitidine

Hypomethylating agents are a classical frontline low-intensity therapy for older patients with acute myeloid leukemia. Recently, TP53 gene mutations have been described as a potential predictive biomarker of better outcome in patients treated with a ten-day decitabine regimen., However, functional c...

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Detalhes bibliográficos
Principais autores: Pierre Bories, Naïs Prade, Stéphanie Lagarde, Bastien Cabarrou, Laetitia Largeaud, Julien Plenecassagnes, Isabelle Luquet, Véronique De Mas, Thomas Filleron, Manon Cassou, Audrey Sarry, Luc-Matthieu Fornecker, Célestine Simand, Sarah Bertoli, Christian Recher, Eric Delabesse, Francesco Bertolini
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2020-01-01
coleção:PLoS ONE
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529302/?tool=EBI
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