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Intrinsic thermal sensing controls proteolysis of Yersinia virulence regulator RovA.

Pathogens, which alternate between environmental reservoirs and a mammalian host, frequently use thermal sensing devices to adjust virulence gene expression. Here, we identify the Yersinia virulence regulator RovA as a protein thermometer. Thermal shifts encountered upon host entry lead to a reversi...

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Bibliografiske detaljer
Principais autores: Katharina Herbst, Matthias Bujara, Ann Kathrin Heroven, Wiebke Opitz, Martin Weichert, Ariane Zimmermann, Petra Dersch
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2009-05-01
Serier:PLoS Pathogens
Online adgang:http://europepmc.org/articles/PMC2676509?pdf=render
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