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Differential trigeminovascular nociceptive responses in the thalamus in the familial hemiplegic migraine 1 knock-in mouse: A Fos protein study

Familial hemiplegic migraine type 1 (FHM-1) is a monogenic subtype of migraine with aura caused by missense mutations in the CACNA1A gene, which encodes the pore-forming α1 subunit of voltage-gated neuronal CaV2.1 (P/Q-type) calcium channels. Transgenic knock-in mice expressing the CACNA1A R192Q mut...

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Principais autores: JungWook Park, HeuiSoo Moon, Simon Akerman, Philip R. Holland, Michele P. Lasalandra, Anna P. Andreou, Michel D. Ferrari, Arn M.J.M. van den Maagdenberg, Peter J. Goadsby
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014-04-01
coleção:Neurobiology of Disease
Assuntos:
Migraine
Aura
Trigeminovascular
Familial hemiplegic migraine
CACNA1A
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0969996113003409
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