Retinoic acid and FGF10 promote the differentiation of pluripotent stem cells into salivary gland placodes

Abstract Background Salivary glands produce saliva that play essential roles in digestion and oral health. Derivation of salivary gland organoids from pluripotent stem cells (PSCs) provides a powerful platform to model the organogenesis processes during development. A few studies attempted to differ...

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Autors principals:	Siqi Zhang, Yi Sui, Shuang Yan, Yifei Zhang, Chong Ding, Xiaodong Su, Jingwei Xiong, Shicheng Wei
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2022-07-01
Col·lecció:	Stem Cell Research & Therapy
Matèries:	Pluripotent stem cells Three-dimensional cultures Salivary glands Organogenesis Modeling
Accés en línia:	https://doi.org/10.1186/s13287-022-03033-5
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