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Nanoparticle Formulations of Poly (ADP-ribose) Polymerase Inhibitors for Cancer Therapy

A number of poly(ADP-ribose) polymerase (PARP) inhibitors have been recently approved for clinical use in BRCA mutated and other cancers. However, off-target toxicity of PARP inhibitors and the emergence of drug resistance following prolonged administration of these inhibitors indicate the need for...

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Autori principali: Bijay Singh, Shicheng Yang, Apurva Krishna, Srinivas Sridhar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020-11-01
Serie:Frontiers in Chemistry
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Accesso online:https://www.frontiersin.org/articles/10.3389/fchem.2020.594619/full
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