Glucocorticoids injure the airway epithelial barrier via endoplasmic reticulum stress-related apoptosis in asthma

IntroductionGlucocorticoids serve as the first-line clinical treatment for asthma; however, 5%–10% of asthma patients respond poorly to glucocorticoids, and their underlying mechanism remains unclear. We investigated whether glucocorticoids can induce airway epithelial endoplasmic reticulum (ER) str...

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Auteurs principaux:	Hao You, Wenjing Zou, Kunpeng Wang, Tangqiaochu Gan, Jie Hu, Wen Tan, Ting Wang, Luo Ren, Gang Geng, Zhou Fu, Chao Niu
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2026-05-01
Collection:	Frontiers in Pharmacology
Sujets:	airway epithelium apoptosis asthma endoplasmic reticulum stress glucocorticoids
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fphar.2026.1771751/full
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