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USP17L13 Enhances Influenza a Virus Replication by Mediating the Degradation of RIG-I and MDA5

The innate immune system, particularly the retinoic acid-inducible gene I (RIG-I)-like receptor (RLR) signaling pathway, is a major early defense barrier against influenza A virus infection. However, excessive immune responses can trigger lethal cytokine storms and severe immune-mediated pathology....

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Principais autores: Yaping Zhang, Chen Qin, Yichao Zhuang, Lei Chen, Xianying Zeng, Li Jiang, Chengjun Li, Hualan Chen, Huihui Kong
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2026-05-01
סדרה:Viruses
נושאים:
influenza
USP17L13
IFN
RIG-I
MDA5
גישה מקוונת:https://www.mdpi.com/1999-4915/18/5/575
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