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Microinjection of antisense oligonucleotides into living mouse testis enables lncRNA function study

Abstract Background Long non-coding RNAs (lncRNAs) have been the focus of ongoing research in a diversity of cellular processes. LncRNAs are abundant in mammalian testis, but their biological function remains poorly known. Results Here, we established an antisense oligonucleotides (ASOs)-based targe...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Zhaohui Chen, Li Ling, Xiaolian Shi, Wu Li, Huicong Zhai, Zhenlong Kang, Bangjin Zheng, Jiaqi Zhu, Suni Ye, Hao Wang, Lingxiu Tong, Juan Ni, Chaoyang Huang, Yang Li, Ke Zheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2021-12-01
Schriftenreihe:Cell & Bioscience
Schlagworte:
lncRNA (long non-coding RNA)
Tsx
ASO (antisense oligonucleotide)
Knock down
Testis injection
Online-Zugang:https://doi.org/10.1186/s13578-021-00717-y
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