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Absence of calcium-sensing receptor basal activity due to inter-subunit disulfide bridges

Abstract G protein-coupled receptors naturally oscillate between inactive and active states, often resulting in receptor constitutive activity with important physiological consequences. Among the class C G protein-coupled receptors that typically sense amino-acids and their derivatives, the calcium...

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Bibliografische Detailangaben
Hauptverfasser: Shumin Ma, Xueliang Yin, Jean-Philippe Pin, Philippe Rondard, Ping Yi, Jianfeng Liu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2024-04-01
Schriftenreihe:Communications Biology
Online-Zugang:https://doi.org/10.1038/s42003-024-06189-3
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