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The assessment of the potential hepatotoxicity of new drugs by in vitro metabolomics

Drug hepatotoxicity assessment is a relevant issue both in the course of drug development as well as in the post marketing phase. The use of human relevant in vitro models in combination with powerful analytical methods (metabolomic analysis) is a promising approach to anticipate, as well as to unde...

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Principais autores: Guillermo Quintás, José V. Castell, Marta Moreno-Torres
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-05-01
coleção:Frontiers in Pharmacology
Assuntos:
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2023.1155271/full
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