Disrupted Blood‐Brain Barrier and Mitochondrial Impairment by Autotaxin–Lysophosphatidic Acid Axis in Postischemic Stroke

Background The loss of endothelial integrity increases the risk of intracerebral hemorrhage during ischemic stroke. Adjunct therapeutic targets for reperfusion in ischemic stroke are in need to prevent blood‐brain barrier disruption. Recently, we have shown that endothelial permeability is mediated...

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Detalhes bibliográficos

Principais autores:	Susmita Bhattarai, Sudha Sharma, Hosne Ara, Utsab Subedi, Grace Sun, Chun Li, Md. Shenuarin Bhuiyan, Christopher Kevil, William P. Armstrong, Miles T. Minvielle, Sumitra Miriyala, Manikandan Panchatcharam
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2021-09-01
Colecção:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Assuntos:	autotaxin blood‐brain barrier ischemic stroke lysophosphatidic acid permeability superoxide radicals
Acesso em linha:	https://www.ahajournals.org/doi/10.1161/JAHA.121.021511
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