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De novo biosynthesis and nicotinamide biotransformation of nicotinamide mononucleotide by engineered yeast cells

Abstract β‐Nicotinamide mononucleotide (NMN) is a precursor of NAD+ in mammals. Research on NAD+ has demonstrated its crucial role against aging and disease. Here two technical paths were established for the efficient synthesis of NMN in the yeast Pichia pastoris, enabling the production of NMN from...

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Principais autores: Yanna Ren, Bei Han, Shijie Wang, Xingbin Wang, Qi Liu, Menghao Cai
格式: Artigo
語言:Inglês
出版: Wiley 2024-11-01
叢編:Microbial Biotechnology
在線閱讀:https://doi.org/10.1111/1751-7915.70048
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