Impact of genetic variants within serotonin turnover enzymes on human cerebral monoamine oxidase A in vivo

Abstract Variants within the monoamine oxidase A (MAO-A, MAOA) and tryptophan hydroxylase 2 (TPH2) genes, the main enzymes in cerebral serotonin (5-HT) turnover, affect risk for depression. Depressed cohorts show increased cerebral MAO-A in positron emission tomography (PET) studies. TPH2 polymorphi...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Marie Spies, Matej Murgaš, Chrysoula Vraka, Cecile Philippe, Gregor Gryglewski, Lukas Nics, Theresa Balber, Pia Baldinger-Melich, Annette M. Hartmann, Dan Rujescu, Marcus Hacker, Edda Winkler-Pjrek, Dietmar Winkler, Rupert Lanzenberger
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group 2023-06-01
Serija:	Translational Psychiatry
Online dostop:	https://doi.org/10.1038/s41398-023-02506-2
Oznake:	Označite Brez oznak, prvi označite!