Genome-wide redistribution of BRD4 binding sites in transformation resistant cells

Hutchinson–Gilford progeria syndrome (HGPS) patients do not develop cancer despite a significant accumulation of DNA damage in their cells. We have recently reported that HGPS cells are refractory to experimental oncogenic transformation and we identified the bromodomain-containing 4 protein (BRD4)...

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Autors principals:	Han Si, Paola Scaffidi, Anand Merchant, Maggie Cam, Eric Stahlberg, Tom Misteli, Patricia Fernandez
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2015-03-01
Col·lecció:	Genomics Data
Matèries:	Progeria BRD4 ChIP-sequencing Tumor protection
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2213596014001184
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