Elevated Nicotinamide Phosphoribosyl Transferase in Skeletal Muscle Augments Exercise Performance and Mitochondrial Respiratory Capacity Following Exercise Training

Mice overexpressing NAMPT in skeletal muscle (NamptTg mice) develop higher exercise endurance and maximal aerobic capacity (VO2max) following voluntary exercise training compared to wild-type (WT) mice. Here, we aimed to investigate the mechanisms underlying by determining skeletal muscle mitochondr...

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Autori principali:	Bram Brouwers, Natalie A. Stephens, Sheila R. Costford, Meghan E. Hopf, Julio E. Ayala, Fanchao Yi, Hui Xie, Jian-Liang Li, Stephen J. Gardell, Lauren M. Sparks, Steven R. Smith
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2018-06-01
Serie:	Frontiers in Physiology
Soggetti:	nicotinamide phosphoribosyl transferase skeletal muscle physiology mitochondrial respiratory capacity maximal aerobic capacity exercise physiology microarray
Accesso online:	https://www.frontiersin.org/article/10.3389/fphys.2018.00704/full
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