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Distinct roles of chronotype, daytime napping, and sleep duration in biological and functional aging: a univariable and multivariable Mendelian randomization study

Abstract Background Sleep traits have been linked to aging, but observational designs cannot separate correlated sleep behaviors or establish causality. We used Mendelian randomization (MR) to estimate both total and direct effects of chronotype, daytime napping, and sleep duration on multidimension...

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Principais autores: Zheng Zhang, Xinglian Wang, Haitang Qiu, Qinghua Luo, Chenggang Jiang, Guang Yang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-03-01
Serier:Clinical Epigenetics
Fag:
Chronotype
Daytime napping
Sleep duration
Biological aging
Epigenetic clock
Mendelian randomization
Online adgang:https://doi.org/10.1186/s13148-026-02068-2
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