Combined mutations of <it>ASXL1, CBL, FLT3, IDH1, IDH2, JAK2, KRAS, NPM1, NRAS, RUNX1, TET2 </it>and <it>WT1 </it>genes in myelodysplastic syndromes and acute myeloid leukemias

<p>Abstract</p> <p>Background</p> <p>Gene mutation is an important mechanism of myeloid leukemogenesis. However, the number and combination of gene mutated in myeloid malignancies is still a matter of investigation.</p> <p>Methods</p> <p>We searched for mutations in the <it>ASXL1, CBL, FLT3, IDH1, I...

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Auteurs principaux:	Vey Norbert, Olschwang Sylviane, Tadrist Zoulika, Nezri Meyer, Murati Anne, Raynaud Stéphane, Trouplin Virginie, Carbuccia Nadine, Rocquain Julien, Birnbaum Daniel, Gelsi-Boyer Véronique, Mozziconacci Marie-Joelle
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2010-08-01
Collection:	BMC Cancer
Accès en ligne:	http://www.biomedcentral.com/1471-2407/10/401
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