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Defective differentiation of adipose precursor cells from lipodystrophic mice lacking perilipin 1.

Perilipin 1 (Plin1) localizes at the surface of lipid droplets to regulate triglyceride storage and hydrolysis in adipocytes. Plin1 defect leads to low adiposity in mice and partial lipodystrophy in human. This study investigated the roles of Plin1 in adipocyte differentiation. Plin1 null (-/-) mice...

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Principais autores: Ying Lyu, Xueying Su, Jingna Deng, Shangxin Liu, Liangqiang Zou, Xiaojing Zhao, Suning Wei, Bin Geng, Guoheng Xu
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2015-01-01
סדרה:PLoS ONE
גישה מקוונת:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0117536&type=printable
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