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Improving 3D Genome Reconstructions Using Orthologous and Functional Constraints.

The study of the 3D architecture of chromosomes has been advancing rapidly in recent years. While a number of methods for 3D reconstruction of genomic models based on Hi-C data were proposed, most of the analyses in the field have been performed on different 3D representation forms (such as graphs)....

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Detalhes bibliográficos
Principais autores: Alon Diament, Tamir Tuller
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2015-05-01
coleção:PLoS Computational Biology
Acesso em linha:https://doi.org/10.1371/journal.pcbi.1004298
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