Characterization and mitigation of gene expression burden in mammalian cells
The design of genetic networks in mammalian cells is still slow and often fails. Here the authors show that miRNA-based incoherent feedforward loop circuits can be used to alleviate cellular burden.
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Portfolio
2020-09-01
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| Σειρά: | Nature Communications |
| Διαθέσιμο Online: | https://doi.org/10.1038/s41467-020-18392-x |
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