A sexually dimorphic hepatic cycle of periportal VLDL generation and subsequent pericentral VLDLR-mediated re-uptake

Abstract Recent single-cell transcriptomes revealed spatiotemporal programmes of liver function on the sublobular scale. However, how sexual dimorphism affected this space-time logic remained poorly understood. We addressed this by performing scRNA-seq in the mouse liver, which revealed that sex, sp...

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Hauptverfasser:	Tomaz Martini, Cédric Gobet, Andrea Salati, Jérôme Blanc, Aart Mookhoek, Michael Reinehr, Graham Knott, Jessica Sordet-Dessimoz, Felix Naef
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2024-09-01
Schriftenreihe:	Nature Communications
Online-Zugang:	https://doi.org/10.1038/s41467-024-52751-2
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