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CTX-M β-Lactamase Production and Virulence of Escherichia coli K1

We report a patient with neonatal meningitis caused by a CTX-M-1–producing Escherichia coli K1 strain. The influence of CTX-M production on virulence was investigated in cell culture and a newborn mouse model of meningitis. CTX-M production had no influence on virulence but was a major factor in cli...

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Principais autores: Damien Dubois, Nemani V. Prasadarao, Rahul Mittal, Laurent Bret, Marie Roujou-Gris, Richard Bonnet
Format: Artigo
Sprog:Inglês
Udgivet: Centers for Disease Control and Prevention 2009-12-01
Serier:Emerging Infectious Diseases
Fag:
Escherichia coli
CTX-M
extended-spectrum β-lactamase
antimicrobial resistance
virulence
meningitis
Online adgang:https://wwwnc.cdc.gov/eid/article/15/12/09-0928_article
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