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The Modulation of Cholesterol Metabolism Is Involved in the Antiviral Effect of Nitazoxanide

We previously investigated the role of Nitazoxanide (NTZ), a thiazolide endowed with antiviral and antiparasitic activity, in HIV-1 infection. NTZ treatment in primary isolated PBMCs was able to reduce HIV-1 infection in vitro by inducing the expression of a number of type-I interferon-stimulated ge...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Claudio Fenizia, Salomè Valentina Ibba, Claudia Vanetti, Sergio Strizzi, Jean-François Rossignol, Mara Biasin, Daria Trabattoni, Mario Clerici
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2021-07-01
Schriftenreihe:Infectious Disease Reports
Schlagworte:
nitazoxanide
thiazolide
cholesterol metabolism
antiviral
FLU
interferon
Online-Zugang:https://www.mdpi.com/2036-7449/13/3/60
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