Anticholinesterase activity of β-carboline-1,3,5-triazine hybrids

Abstract The β-carboline-1,3,5-triazine hydrochlorides 8-13 were evaluated in vitro against acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). The analysed compounds were selective to BuChE, with IC50 values in the range from 1.0-18.8 µM being obtained. The N-{2-[(4,6-dihydrazinyl-1,3,5-...

Cijeli opis

Bibliografski detalji

Glavni autori:	Paula Baréa, Valéria Aquilino Barbosa, Diego Alberto dos Santos Yamazaki, Carla Maria Beraldi Gomes, Claudio R. Novello, Willian Ferreira da Costa, Gisele de Freitas Gauze, Maria Helena Sarragiotto
Format:	Artigo
Jezik:	Inglês
Izdano:	Universidade de São Paulo, Faculdade de Ciências Farmacêuticas 2022-07-01
Serija:	Brazilian Journal of Pharmaceutical Sciences
Teme:	β-carboline. 1,3,5-triazine. Acetylcholinesterase. Butyrylcholinesterase
Online pristup:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100650&tlng=en
Oznake:	Dodaj oznaku Bez oznaka, Budi prvi tko označuje ovaj zapis!