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STINGing the immune system: lessons learned through a model of G34-mutant pediatric high-grade glioma

Pediatric high-grade gliomas (pHGGs) are aggressive diseases with poor outcomes. The diverse molecular heterogeneity in these rare tumors and inadequate tumor models have limited the development of effective therapies. In this issue of the JCI, Haase et al. produced a genetically engineered mouse mo...

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Principais autores: Connor P. Hall, James C. Cronk, Jeffrey A. Rubens
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2022-11-01
叢編:The Journal of Clinical Investigation
在線閱讀:https://doi.org/10.1172/JCI164420
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