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Characteristics of sodium and water retention in rats with nephrotic syndrome induced by puromycin aminonucleoside

Abstract Introduction Nephrotic syndrome (NS) is characterized by renal sodium and water retention. The mechanisms are not fully elucidated. Methods The NS rat model was established by single intraperitoneal injection of 100 mg/kg puromycin aminonucleoside (PAN). The plasma electrolyte level and uri...

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Principais autores: Zaiping Xu, Yunlai Wang, Ye Feng, Mo Yang, Gaoxiang Shi, Zihua Xuan, Fan Xu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-10-01
Serier:BMC Nephrology
Fag:
Nephrotic syndrome
Sodium and water retention
Urinary sodium excretion
Epithelial Na+ channel
Aquaporin 2
Online adgang:https://doi.org/10.1186/s12882-023-03367-z
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